Gibeleko erradioenbolizazioaren CFD simulazioak: odolaren biskositatearen eragina gibeleko hemodinamikan eta mikroesferen distribuzioan
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Erradioenbolizazioa (RE) gibeleko minbizia tratatzeko metodoetako bat da. Bertan, mikrokateter bidez gibeleko arterian mikroesfera erradioaktiboak injektatzen dira, hauek tumoreak enbolizazio eta erradiazio bidez erasotzeko. Mikroesferen ibilbidea ordenagailu bidezko fluido dinamika simulazioekin (CFD) aztertu daiteke. Kalkulu hauen iraupen luzea arazo bat da medikuntzaren egunerokotasunean simulazioak erabili ahal izateko. Kalkuluak azkartzeko asmoz, odolaren biskositatearen izaera ez-newtondarra izaera newtondarrera sinplifikatu da. Emaitzek erakutsi dute mikroesferen banaketan eta odolaren hemodinamikan biskositate aldakorraren eragina mespretxagarria dela, odola fluido newtondar bezala aztertzearen sinplifikazioa ontzat emanez.
Radioembolization (RE) is a treatment for patients with liver cancer. RE consists of the infusion of radioactive microspheres in the hepatic artery using a microcatheter. Microspheres treat tumors by embolization and radiation. The trajectory of the microspheres can be analyzed using computational fluid dynamics simulations (CFD). The long duration of these calculations supposes a problem for their use in the clinical setting. To decrease the simulation time, blood, a non-Newtonian fluid, was considered as a Newtonian fluid. Results show that microsphere distribution and blood flow characteristics barely change when using a Newtonian fluid approach vs. a non-Newtonian fluid approach.
Radioembolization (RE) is a treatment for patients with liver cancer. RE consists of the infusion of radioactive microspheres in the hepatic artery using a microcatheter. Microspheres treat tumors by embolization and radiation. The trajectory of the microspheres can be analyzed using computational fluid dynamics simulations (CFD). The long duration of these calculations supposes a problem for their use in the clinical setting. To decrease the simulation time, blood, a non-Newtonian fluid, was considered as a Newtonian fluid. Results show that microsphere distribution and blood flow characteristics barely change when using a Newtonian fluid approach vs. a non-Newtonian fluid approach.
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erradioenbolizazioa, gibeleko minbizia, odolaren biskositatea, fluido newtondar eta ez-newtondarrak., radioembolization, liver cancer, blood viscosity, Newtonian and no-Newtonian fluids.