Euskal estuarioetako sedimentuetako mikroorganismo harizpidunen aniztasuna: Genomen analisia ikuspuntu bioteknologikotik

Abstract

Itsas inguruneetan mikroorganismo-aniztasun handia dago. Mikroorganismo horien genomek estres-baldintzetara egokitzea ahalbidetzen diete, hala nola gatz-kontzentrazio handiak eta elikagai-eskasia, zein polimero konplexuak degradatzea. Ezaugarri horiei esker, itsas mikroorganismoak tresna bioteknologiko berriak garatzeko iturri baliotsua dira. Lan honetan, euskal kostaldeko estuarioetako sedimentuetatik mikrobio harizpidunak isolatu eta fenotipikoki karakterizatu dira, polisakarido konplexuak degradatzeko edo/eta ingurunera pigmentuak jariatzeko gaitasunean oinarrituta. Hala, intereseko hiru espezieren genomak lehen aldiz sekuentziatu dira, eta haien CAZyme-en zein metabolito sekundarioen gene-multzoen azterketak iradokitzen du jarduera entzimatiko berrien eta metabolito sekundarioen iturri gisa erabil daitezkeela.Marine environments are rich in microbial diversity. Marine microbes have developed genomic resources to adapt to stress conditions, such as high salt concentrations and nutrient scarcity, or to degrade complex polymeric substrates. These features make marine microbes a very valuable resource in the field of biotechnology. In this study, filamentous microbes from sediments of Basque estuaries where isolated and phenotypically characterized based on the capacity to degrade complex polysaccharides or/and secrete pigments to the culture medium. Thus, in this study the genomes of three isolates of interest are reported for the first time and their CAZymes well as secondary metabolite gene cluster analyses suggest that they could be used as a source of novel enzymatic activities and secondary metabolites.